Measurement of Cartilage Deformation in Intact Knee Joints under Compressive Loading

Authors

  • Balsam Muqdad Rashid Biomedical Engineering Department, Al-Nahrain University
  • Sadiq Jaafar Hamandi Biomedical Engineering Department, Al-Nahrain University
  • Eman Ghadban Khalil Biomedical Engineering Department, Al-Nahrain University

DOI:

https://doi.org/10.29194/NJES.25010044

Keywords:

Articular Cartilage, Meniscus Cartilage, Compressive Test, Mechanical Characteristics, Failure, Force Break

Abstract

Many joints in the body depend on cartilage for their mechanical function. Since cartilage lacks the ability to self-heal when injured, treatments and replacements for damaged cartilage have been created in recent decades. The mechanical tests had an important role in the treatment and designing of the replaced cartilage. There are two types of cartilages in the knees: fibrocartilage (the meniscus, it is a special type of cartilage) and hyaline cartilage. Its mechanical properties are important because structural failure of cartilage is closely related with joint disorders. This study aimed to determine the stress-strain curve to give broader understanding of the material’s properties. The results of this study could help to develop computational models for evaluating mechanics of knee joint, predicting possible failure locations and disease progression in joints.
The study involved two specimens taken from bovine, the first was the articular cartilage with subchondral bone and the second was the meniscus cartilage each one loaded on a compressive testing machine to compute the displacement, and the force applied, enabling the calculation of the stress-strain curve of the material.
Specimen failure occurred in the articular cartilage surface at a force break of 73.8N and get force peak about 87.2 N. The meniscus cartilage failure had occurred at a force break of 29.2 N and get force peak about 34.9 N.

Downloads

Download data is not yet available.

References

J. H. Lai and M. E. Levenston, “Meniscus and cartilage exhibit distinct intra-tissue strain distributions under unconfined compression,” Osteoarthr. Cartil., vol. 18, no. 10, pp. 1291–1299, 2010.

E. K. Danso, J. T. J. Honkanen, S. Saarakkala, and R. K. Korhonen, “Comparison of nonlinear mechanical properties of bovine articular cartilage and meniscus,” J. Biomech., vol. 47, no. 1, pp. 200–206, 2014.

A. C. Aufderheide and K. A. Athanasiou, “A direct compression stimulator for articular cartilage and meniscal explants,” Ann. Biomed. Eng., vol. 34, no. 9, pp. 1463–1474, 2006.

McNulty, Amy L., and Farshid Guilak, “Mechanobiology of the meniscus,”Journal of biomechanics, vol. 48, no.8, pp. 1469-1478, 2015.

Mcculloch PC, Jones HL, Hamilton K, Hogen MG and Gold JE, Noble PC, “Does simulated walking cause gapping of meniscal repairs?,” J Exp Orthop., vol.3, no.11, pp.1-10, 2016.

L. J. Bonassar, A. J. Grodzinsky, E. H. Frank, S. G. Davila, N. R. Bhaktav, and S. B. Trippel, “The effect of dynamic compression on the response of articular cartilage to insulin-like growth factor-I,” J. Orthop. Res., vol. 19, no. 1, pp. 11–17, 2001.

Camarero-Espinosa, S., Rothen-Rutishauser, B., Foster, E. J., and Weder, C., “Articular cartilage: from formation to tissue engineering,” Biomaterials science, vol.4, no.5, pp.734-767, 2016.

Abusara, Z., Von Kossel, M., and Herzog, W, “In vivo dynamic deformation of articular cartilage in intact joints loaded by controlled muscular contractions,” Plos one, voi.11, no.1, pp.1-12, 2016.

J. M. Mansour, “Biomechanics of cartilage,” Kinesiol. Mech. Pathomechanics Hum. Mov. Second Ed., pp. 69–83, 2013.

M. T. Hirschmann and W. Müller, “Complex function of the knee joint?: the current understanding of the knee,” Knee Surgery, Sport. Traumatol. Arthrosc., vol. 23, no. 10, pp. 2780–2788, 2015.

D. Olvera, A. Daly, and D. J. Kelly, “Mechanical testing of cartilage constructs,” Methods Mol. Biol., vol. 1340, pp. 279–287, 2015.

K. M. Clements, Z. C. Bee, G. V. Crossingham, M. A. Adams, and M. Sharif, “How severe must repetitive loading be to kill chondrocytes in articular cartilage?,” Osteoarthr. Cartil., vol. 9, no. 5, pp. 499–507, 2001.

H. Mahmood, D. E. T. Shepherd, and D. M. Espino, “Surface damage of bovine articular cartilage-off-bone: The effect of variations in underlying substrate and frequency,” BMC Musculoskelet. Disord., vol. 19, no. 1, pp. 1–11, 2018.

R. I. Abed, S. J. Abbass, and W. A. Alsaadan, “Testing mechanical behaviour of bone-plate construct,” 2020 3rd Int. Conf. Eng. Technol. its Appl. IICETA 2020, pp. 220–225, 2020.

J. P. A. Arokoski, J. S. Jurvelin, U. Väätäinen, and H. J. Helminen, “Normal and pathological adaptations of articular cartilage,” Med. Sci. Sport, vol. 10, no. 1, pp. 186–198, 2000.

T. P. Andriacchi, A. Mundermann, R. L. E. J. A. Smith, C. O. and S. K. Dyrby, “A Framework for the in VivoPathomechanics of Osteoarthritis at the Knee,” Ann. Biomed. Eng., vol. 32, no. 3, pp. 447–457, 2004.

David Roylance, “Stress-strain curve,” Fibre Met. Laminates, pp. 1–14, 2001.

H. Sadeghi, D. M. Espino, and D. E. T. Shepherd, “Fatigue strength of bovine articular cartilage-on-bone under three-point bending the effect of loading frequency,” BMC Musculoskelet. Disord., vol. 18, no. 1, pp. 1–8, 2017.

Korhonen, R. K., Laasanen, M. S., Töyräs, J., Rieppo, J., Hirvonen, J., Helminen, H. J., and Jurvelin, J. S., “Comparison of the equilibrium response of articular cartilage in unconfined compression, confined compression and indentation,” Journal of biomechanics, vol. 35, no.7, pp. 903-909, 2002.

A. Abdelgaied, M. Stanley, M. Galfe, H. Berry, E. Ingham and J. Fisher, “Comparison of the biomechanical tensile and compressive properties of decellularised and natural porcine meniscus,” Journal of Biomechanics, vol. 48, pp. 1389-1396. 2015.

Downloads

Published

03-04-2022

How to Cite

[1]
B. M. Rashid, S. J. Hamandi, and E. G. Khalil, “Measurement of Cartilage Deformation in Intact Knee Joints under Compressive Loading”, NJES, vol. 25, no. 1, pp. 44–48, Apr. 2022, doi: 10.29194/NJES.25010044.

Similar Articles

1-10 of 226

You may also start an advanced similarity search for this article.