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Go to Editorial ManagerArtificial intelligence (AI) is rapidly advancing as a valuable tool in oncology for enhancing detection and management of cancer. The integration of AI with PET/CT imaging presents significant scenarios for improving efficiency and accuracy of cancer diagnosis. This study examines the current applications of AI with PET/CT imaging, highlighting its role in diagnosing, differentiating, delineating, staging, assessing therapy response, determining prognosis, and enhancing image quality. A comprehensive literature search was conducted in six data-bases to get the most recent works, use Springer, Scopus, PubMed, Web of Science, IEEE, and Google Scholar in the last five years (2019-2024), identifying 80 studies that met the criteria for inclusion that focused on AI-driven models applied to PET/CT data in various cancers, with lung cancer being the most studied. Other cancers examined include head and neck, breast, lymph nodes, whole body, and others. All studies involved human subjects. The findings indicate that AI holds promise in improving cancer detection, identifying benign from malignant tumors, aiding in segmentation, response evaluation, staging, and determining the prognosis. However, the application of AI-powered models and PET/CT-derived radiomics in clinical practice is limited because of issues of data normalization, reproducibility, and the requirement of large multi-center data sets for improving model generalizability. All these limitations have to be solved to guarantee the dependable and ethical use of AI in day-to-day clinical activities.
Kidney disease is a global health concern, often leading to kidney failure and impaired function. Artificial intelligence and deep learning have been extensively researched, with numerous proposed models and methods to improve kidney disease diagnosis. This work aims to enhance the efficiency and accuracy of the diagnostic system for kidney disease by using Deep Learning, thereby contributing to effective healthcare delivery. This work proposed three models: CNN, CNN-XGBoost and CNN-RF to extract features and classify kidney Ultrasound images into four categories: three abnormal cases (stones, hydronephrosis, and cysts) and one normal case. The models were tested on a real dataset of 1260 kidney ultrasound images (from 1000 patients) collected from the Lithotripsy Centre in Iraq. CNN models are often viewed as black boxes due to the challenge of understanding their learned behaviors, Visualizing Intermediate Activations (VIA) was used to address this issue. The proposed framework was assessed based on precision, recall, F1-score, and accuracy. CNN-RF is the most accurate model, with an accuracy of 99.6%. This study can potentially assist radiologists in high-volume medical facilities and enhance the accuracy of the diagnostic system for kidney disease.
Thyroid nodules (TNs) are discrete abnormalities located within the thyroid gland that are radiologically different from the surrounding thyroid tissue. Ultrasound is an accurate and efficient way to diagnose thyroid nodules. Recently, several methods of AI were proposed to improve the detection of thyroid nodules ultrasound images with good performances. However, in some cases related to the type or size of the dataset using machine or transfer deep learning methods alone is unable to achieve high accuracy and high specificity. Consequently, the addition of feature selection)FS) to the deep learning method enhances the results by reducing the high features and the time needed for training the dataset. This study proposes two deep-learning models for classifying thyroid nodule US images into two categories: benign and malignant. ResNet50 was the first model used to extract deep features from US images. The second model integrates ResNet50 and principal component analysis (PCA) for feature selection, intending to reduce dataset dimensionality while maintaining the greatest data variance possible before classification. The proposed model was created using a freely available dataset. The dataset consists of 800 images, 400 benign and 400 malignant. The suggested system was accessed based on accuracy, precision, recall, and F1 score. The classification accuracy for ResNet50 was 85%, while ReNet50-PCA was 89.16%. The combination of deep learning and FS techniques in this research produces an interesting diagnostic framework that can potentially increase efficiency and accuracy in thyroid cancer detection, especially in local healthcare centers.
Technically, medical imaging modalities are quantitative, qualitative, and semi-quantitative. Such modalities can generate meaningful and valuable quantitative and qualitative data. Correlating predictive outcomes with quantitative and qualitative data is a difficult process. Thanks to modern computational hardware and advanced machine learning algorithms, it is not a demanding job to perform predictive analysis by cultivating quantitative and qualitative data. Radiomics is a popular topic that studies quantitative data from medical images in order to obtain biologically meaningful information for diagnosis, prognosis, theragnosis, and decision support. Handcrafted radiomics is a process including features based on shape, pixel, and texture-related knowledge from medical scans. In the pursuit of advancing the field of radiomics, we have developed a cutting-edge radiomics training simulator, powered by MATLAB. This tool has been designed for those familiar with MATLAB, making it easy for them to transition into the fascinating world of radiomics. MATLAB's user-friendly interface and strong support in the engineering community provide an ideal platform for this simulator, ensuring aspiring radiomics learners have access to the resources they need for success. Throughout the paper, purpose, design details and methodology of the simulator are described.
Optical coherence tomography (OCT) allows for direct and immediate imaging of the morphology of retinal tissue. It has become a crucial imaging modality for diagnosing eye problems in ophthalmology. One of the most significant morphological characteristics of the retina is the structure of the retinal layers, which provides important evidence for diagnostic purposes and is related to a variety of retinal diseases. In this paper, a convolutional neural network (CNN) model is proposed that can identify the difference between a normal retina and three common macular diseases: Diabetic macular edema (DME), Drusen, and Choroidal neovascularization (CNV). This proposed model was trained and tested on an open source dataset of OCT images also with professional disease classifications such as DME, CNV, Drusen, and Normal. The suggested model has achieved 98.3% overall classification accuracy, with only 7 wrong classifications out of 368 test samples. The suggested model significantly outperforms other models that made use of the identical dataset. The final results show that the suggested model is particularly adapted to the detection of retinal disorders in ophthalmology centers.
Breast cancer is one of the greatest frequent tumours among females in Iraq. Medical ultrasound imaging has become a common modality for breast tumour imaging because of its ease of use, low cost, and safety. In the present study, Convolutional Neural Network (CNN) feature extraction approaches were used to classify breast ultrasound imaging. The CNN model used is composed of four-layer for breast cancer ultrasound image analysis. Two types of free datasets were used. These data were divided into groups A and B. Group A has three classes, namely benign, malignant and normal, while group B has two classes, namely, benign and malignant. The proposed technique was assessed based on its accuracy, precision, F1 score and recall. The model's classification accuracy for data A was 96%, whereas for data B was 100%.
Continuous Positive Airway Pressure (CPAP) ventilation remains a mainstay treatment for different respiratory disorders. Good pressure stability and pressure reduction during exhalation are of major importance condition to ensure the clinical efficacy and comfort of CPAP therapy. Obstructive Sleep Apnea (OSA) and today coronavirus (COVID-19) are the main two diseases mitigated by the CPAP. This paper introduced a systematic review of the CPAP design in terms of the hardware design, Simulation-based CPAP system, control algorithm, and the measured performance. The accuracy is used as measurement of performance and calculated from the pressure value. The accuracy was compared to the predefined U.S. Food and Drug Administration (FDA)-based threshold value in which it considers this value as a reference. The results related to the modern CPAP devices introduced in this study to explain the accuracy of experimental CPAP. These were compared with a commercial CPAP devices. Also, it was revealed how the results coincide with the error ratio defined by the FDA as an evaluation measurement. The FDA error ratio determines the performance of the optimized CPAP device. This work is the first review that presented the knowledge about engineering design of the CPAP system, so it will be the first in the literature.