Vol. 20 No. 1 (2017) Cover Image
Vol. 20 No. 1 (2017)

Published: January 31, 2017

Pages: 176-182

Articles

Detection of tumor mass based on laser scanning imaging

Munqith S. Dawood 1 Eman Ghadhban Khalil 1 Halah Hadi Saleh 1
1 Department of Biomedical Engineering, Al-Nahrain University
History
  • Received: October 1, 2016
  • Available Online: January 1, 2017

Abstract

Optical methods are widely used for medical diagnostic and therapeutic purposes. The use of laser source as non-ionized radiation in the imaging is considered safe, and has advantages more than the other radiological methods The laser application in imaging is based upon the detection and measuring the laser light parameters after passing through the turbid media of the tissue layers and the tumor mass to differentiate them precisely according to their different optical properties._x000D_ In this experimental study, the tumor masses were implanted in the legs of ex-vivo mice. Then each leg was non-invasively scanned by NIR 785nm diode laser. The penetrated laser light power through the leg was measured. The results were tabulated and treated by using the Matlab program version R2013a (8.1.0.609) to create 2D image for the scanned tissue. The resulted images were clear. They showed precisely the imbedded tumor, its dimensions, and its location inside the tissue.

Keywords

References

  1. Robin N. Strickland, "Image-Processing Techniques for Tumor Detection ", University of Arizona, New York, Basel, Marcel Dekker, Inc.2002.
  2. Imaging Radiology Tests, Copyright American Cancer Society 2015.
  3. Harjit Singh, Janet A. Neutze, "Radiology Fundamentals: Introduction to Imaging and Technology", 4nd edition, Springer, New York 2012.
  4. Andrew D. Perron, "Injuries to Bones and Organs", section VІІІ, chapter 69, pp753-763, 2008.
  5. "The radiology information resource for patients", Radiological Society of North America, Inc., pp. 1-7, 2014.
  6. Lars G. Hanson, "Introduction to Magnetic Resonance Imaging Techniques" Danish Research Centre for Magnetic Resonance (DRCMR), Copenhagen University Hospital Hvidovre, 2009.
  7. Leonard Fass, "Imaging and cancer", Molecular oncology, Vol. 2, pp.115–152, Federation of European Biochemical Societies. Published by Elsevier B.V.2008.
  8. Franceschini MA, Moesta KT, Fantini S, Gaida G, Gratton E, Jess H, Mantulin WW, Seeber M, Schlag PM, Kaschke M. "Frequency-domain techniques enhance optical mammography", Proc Natl Acad Sci USA, Vol. 12, pp. 6468-73, 1997.
  9. Bevilacqua F., Piguet D., Marquet P., etc., "In Vivo Local Determination of Tissue Optical Properties: Applications to Human Brain", Appl. Opt., Vol. 38, No. 22, pp. 4939-4950, Aug 1999.
  10. David A. Boas, Constantinos Pitris, Nimmi Ramanujam, "Handbook of biomedical optics", 1stedition, CRC Press Taylor& Francis Group, ISBN9781420090369, 2011.
  11. Sio-IongAo, & Len Gelman. "Electrical Engineering and Applied Computing ., Lecture Notes in Electrical Engineering "Springer, A Case Study Analysis of an E-Business Security Negotiations Support Tool Jason R. C. Nurse, Jane E. Sinclair, pp209-220, 2011.
  12. Hebden JC, Delpy DT. Diagnostic imaging with light,Br J Radiol. Nov;70 Spec No:S206-14. 1997.
  13. Mohammed Mesradi; AurelieGenoux; Vesna Cuplov; DarineAbi-Haidar; Sebastien Jan; Irene Buvat; Frederic Pain. "Experimental and Analytical Comparative Study of Optical Coefficient of Fresh and Frozen Rat Tissues", Journal of Biomedical Optics, Vol. 18(11), 117010, November 2013.
  14. Brian W. Pogue, Markus Testorf, Troy McBride, Ulf Osterberg, Keith Paulsen, "Instrumentation and design of a frequency domain diffuse optical tomography imager for breast cancer detection", OPTICS EXPRESS, Vol. 1, No. 13, pp .391-403,1997.
  15. Victor Chernomordik; David W. Hattery; Dirk Grosenick; HeidrunWabnitz; Herbert Rinneberg; K. Thomas Moesta; Peter M. Schlag; Amir Gandjbakhche. Quantification of optical properties of a breast tumor using random walk theory, J. Biomed. Opt. 7(1), 80-87 (Jan, 2002).
  16. Sergio Fantini, Scott A. Walker, Maria Angela Franceschini, Michael Kaschke, Peter M. Schlag & K. Thomas Moesta, "Assessment of the size, position, and optical properties of breast tumors in vivo by noninvasive optical methods", Applied Optics ,Vol. 37, No. 10, pp.1982-1989, April1998.
  17. T Durduran, R Choe, J P Culver1, L Zubkov1, M J Holboke1, J Giammarco, B Chance & A.G. Yodh, "Bulk optical properties of healthy female breast tissue", Phys. Med. Biol. 47, pp.2847–2861,Jul 2002.